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The events started with the detonation of a sticky bomb — a growing menace in Kabul, where insurgents and criminals slap magnetic bombs on the underside of vehicles.
Despite a winter lull in fighting due to heavy snowfall in the mountains where the Islamist Taliban typically rest and regroup ahead of their annual spring offensive, roadside bombs continue to hit Afghan forces and their foreign allies.
The Britain-based monitor said the car bomb targeted a bustling area located near several restaurants, leading to severe material damage. It was not clear who was behind the attack or if the casualties were all civilians.
The explosion happened in Sourou province near the Mali border as students returned to school after the Christmas holidays, a security source said.
Iran's supreme leader Ayatollah Ali Khamenei blamed "evil and criminal enemies" of the country for the attack and vowed a "harsh response."
At least 12 people were killed and around 50 injured after a series of explosions at a chemical factory in the western Indian state of Maharashtra on Saturday, hospital officials and police said.
The explosion caused a halt to trains in an area called Nordhavn, just north of the city centre. Two people were inside the tax agency's building but both were unharmed, police told Danish broadcaster TV2.
The bloodshed in the capital comes amid an ongoing surge in attacks across Afghanistan, where some 1,500 people were killed or injured last month alone.
No one was injured in the blast, which happened outside a station in the Norrebro, just outside the city centre, police said on Twitter.
Daesh said one of its fighters blew himself up at a "large gathering" in Kabul while others "detonated a parked explosives-laden vehicle" when security forces arrived, in a statement posted on the Telegram messaging app.