Barcelona qualified for the semi-finals of the Champions League after a 3-0 second-leg thrashing of Manchester United at the Camp Nou on Tuesday.
Lionel Messi scored twice in the first half before Philippe Coutinho added the third to clinch a 4-0 aggregate win.
The five-time European champions will face either Liverpool or Porto in the last four in their first appearance at the stage of the competition since 2015.
On the other hand, Ajax stunned Juventus to reach the Champions League semi-finals for the first time since 1997 as Matthijs de Ligt's thumping second-half header secured a 2-1 second-leg victory in the last eight in Turin on Tuesday.
Cristiano Ronaldo, bidding for his sixth Champions League title, scored a 28th-minute header to put Juve ahead after a 1-1 first-leg draw, but Donny van de Beek levelled for the visitors before half-time.
Teenage centre-back De Ligt struck midway through the second period, though, to seal a 3-2 aggregate win and set up a last-four clash with either Manchester City or Tottenham.
The young Dutch side had already eliminated three-time defending champions Real Madrid en route to the quarters, overturning a 2-1 home defeat against the Spanish side with a memorable 4-1 victory at the Santiago Bernabeu.
Juventus had been looking to reach the Champions League semi-finals for the third time in the past five seasons.
But Ronaldo, who scored an away goal last week with a diving header in Amsterdam, was Juve's only weapon against the impressive Dutch side.
The 34-year-old was signed for 100 million euros ($117 million) last summer from Real Madrid in a bid to win the European trophy for the first time since 1996, when they beat Ajax in the final.
Massimiliano Allegri had been forced to reshuffle his side because of injuries, with Paulo Dybala returning in place of the injured Mario Mandzukic, while captain Giorgio Chiellini was also sidelined.
Agencies