ADSCC develops virus-free, clinical-grade stem cells

In a groundbreaking advancement toward cell therapy and regenerative medicine, the Abu Dhabi Stem Cells Centre (ADSCC) has successfully developed clinical-grade induced pluripotent stem cells (iPSCs) that comply with the Good Manufacturing Practice protocols and are, as such, compliant with the strictest international standards for clinical applications.

This has been accomplished by the scientists at ADSCC’s research laboratories in Abu Dhabi using their virus-free in-house, exclusive techniques, know-how and protocols.

The achievement, the first of its kind in the Middle East, positions ADSCC as a pioneer in stem cell research, setting a global benchmark for innovation and safety in precision medicine.

iPSCs are a cutting-edge innovation in biomedical science, to be used for a wide range of therapeutic applications, including the treatment of neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and multiple sclerosis, as well as other conditions such as diabetes. ADSCC is currently running multiple research projects for the use of iPSCs in treating these diseases.

Derived by reprogramming adult cells, such as skin and blood cells, back to an embryonic-like state, iPSCs can differentiate into many types of cells in the human body. Moreover, iPSCs can be created from a patient’s own cells, allowing for autologous, personalised therapies that minimise or even eliminate the risk of immune rejection and the need for immunosuppressive drugs.

Professor Yendry Ventura, CEO of ADSCC, and the Principal Investigator in ADSCC’s Capital Organ Regeneration (CORi) research project, said, “Developing our own clinical-grade iPSCs using a proprietary, virus-free protocol is a monumental step forward for the UAE and the global medical community. This accomplishment not only reinforces Abu Dhabi’s position as a hub for cutting-edge medical research but also opens the door to transformative therapies that can address some of the most complex diseases.”

Professor Angelo Vescovi of the Link Campus University of Rome and Adviser at ADSCC, said, “Induced pluripotent stem cells are a cornerstone of personalised medicine.”

WAM