Ravindra Jadeja, second from right, celebrates after he bowled Shimron Hetmyer at Kensington Oval on Thursday. AP
Beaten 1-0 in the preceding two-Test series, the home team were brushed aside for just 114 off 23 overs after being put in as they appeared completely at sea in trying to cope especially with variations offered by Yadav's wrist-spin.
India were always on course for the modest target thanks to Ishan Kishan's belligerent 52, although the loss of three wickets near the end of the chase took some of the gloss off the win.
In what was clearly a bit of an audition for younger batting aspirants ahead of the World Cup, champion batsman Virat Kohli did not feature while captain Rohit Sharma only appeared at the fall of the fifth wicket.
Brought on as the sixth bowler, Yadav triggered the capitulation which saw the last seven wickets cascading for 26 runs, finishing with the outstanding figures of four for six off three overs.
"I've been working on my rhythm over the last two years. My rhythm wasn't very well last year but now it's coming out very well," said man-of-the-match Yadav.
"With the spin and drift it's very difficult for the batters to read, especially now with an increase in pace."
Jadeja claimed three for 37 to perfectly complement the work of Yadav after seamers Hardik Pandya, debutant Mukesh Kumar and Shardul Thakur had done the early damage with a wicket apiece.
Only captain Shai Hope, who was ninth out for a top score of 43, seemed capable of coping with the varied Indian attack as the West Indies folded for their second-lowest ODI total against India and joint-third lowest ODI total at home.
India are counting down to the hosting of the World Cup in just over two months' time while this latest West Indies batting display will only deepen the gloom in the Caribbean after the team failed to advance to the World Cup following a disastrous qualifying campaign in Zimbabwe in June.
Both teams will depart for Zimbabwe at the end of the series for their World Cup qualifying campaign which begins on June 18. The all-important tournament will confirm the remaining two spots for the 10-team ICC Cricket World Cup 2023, India.
Zaman lifted Pakistan from 21-2 during a third-wicket stand of 154 off 161 balls with Mohammad Rizwan, who made a polished 74-ball 77 with six boundaries.
New Zealand's spinners strangled Pakistan on a turning wicket to win the second ODI by 79 runs Wednesday and level the three-match series 1-1.
The campaign aims to integrate sports into charitable work by harnessing sports in serving charity activities during the Holy Month and positively integrating sports events in serving the community, which contributes to supporting social services and humanitarian projects.
The partial schedule released on Thursday by IPL comprises 21 matches, to be played across 10 cities, with each team playing a minimum of three matches and a maximum of five.
The former Pakistani captain, who has represented 19 teams in the T20 format, scoring 3,698 runs for the national side and 2,398 for the Kings, reached the milestone in 271 innings as opposed to Gayle who achieved the feat in 285 innings.